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Novel Liquid Biopsy Test Verifies Remission In Patients With HPV-Linked Oropharyngeal Cancer

Researchers have developed an extremely responsive blood test with an ability to detect small traces of cancer-specific DNA. This test can precisely verify whether patients with HPV-linked oropharyngeal squamous cell carcinoma (OPSCC) are free from cancer after the completion of their radiation therapy. The results of this research are supposed to be presented at the 60th Annual Meeting of the American Society for Radiation Oncology (ASTRO).

The novel liquid biopsy test can measure fractions of DNA dropped by cancers cells in the blood. This test might help in saving thousands of dollars per patient by minimizing the requirement for expensive radiological tests including PET/CT scans subsequent to radiation therapy. Bhisham Chera, MD, Associate Professor, Radiation Oncology, University of North Carolina, proclaimed that their research team has created an extremely precise and responsive liquid biopsy blood test. This test is supposed to be useful for individuals with HPV-linked OPSCC.

On a similar note, researchers at the University Of Colorado School Of Medicine announced that they have successfully discovered a genetic connection between idiopathic pulmonary fibrosis and rheumatoid arthritis-linked interstitial lung disease. The results of this research can be accessed in the New England Journal of Medicine. Joyce Lee, MD, Associate Professor, Department of Medicine, is the first author of the latest research.

Lee stated that by finding this link in the genetic background between these conditions, the scientists now know that idiopathic pulmonary fibrosis and rheumatoid arthritis-linked interstitial lung disease have similar reasons. So, these conditions might have similar treatment techniques. Rheumatoid arthritis (RA) is an autoimmune and inflammatory disease. It is mostly associated with progressive impairment, increased mortality, and systemic complications. According to the study, about 60% of individuals with RA have to suffer from pulmonary conditions called interstitial lung disease.