Recently, Brazil’s Ministry of Health obtained reports of about 11,524 outbreaks of food-borne diseases between 2000 and 2015. About 219,909 people were found to be fallen ill and about 167 died from the diseases in question. Generally, bacteria are the reason for most of the outbreaks of illnesses such as gastroenteritis and diarrhea. The most ordinary illnesses were because of Salmonella spp., with about 31,700 people detected infected in the period (approximately 14.4% of the total), Staphylococcus aureus (about 7.4%), and Escherichia coli (6.1%).
As per the study by the Ministry of Social Development, bacteria from the genus Salmonella were the causative agents in approximately 42.5% of the laboratory-verified food-borne disease outbreaks noted in Brazil between 1999 and 2009. In an article accessible online in the journal PLOS ONE, the biomedical scientists Fernanda Almeida and Amanda Aparecida Seribelli from the Falcão’s lab explained the process by which they sequenced and inspected genomes. They studied about 90 strains of a particular serotype of Salmonella enteric known as S. Typhimurium.
On a similar note, scientists from the University of Eastern Finland proclaimed that they have discovered novel compounds with an ability to target the bacterial infection. The latest research might potentially offer an answer to the antibiotic resistance. The results of the latest research can be accessed in the journal ChemMedChem. Prasanthi Medarametla, Researcher, University of Eastern Finland, and associates focused on a protein named LsrK, which is found to be involved in the bacterial communication process named quorum sensing. It allows bacteria to colonize, create virulence factors, structure a biofilm, and start an infection.
Therefore, disturbing the process of quorum sensing has become the latest focus in the study of agents that might reduce and inhibit bacteria. In the age of increased antibiotic resistance, focusing on enzymes dealing with the bacterial communication (quorum sensing) highlights a novel strategy for fighting with the bacterial infections.